Cimetidine and theophylline drug interaction

WebThere is undoubtedly considerable interindividual variation in the magnitude of the cimetidine-theophylline interaction, as Ambrose and Harralson suggest. 3. Conrad KA, Nyman OW. Effects of metoprolol and propranolol on theophylline elimination. Clin Pharmacol Ther 1980;28:463-7. 4. Vicuna N, McNay JL, Ludden TM, Schwertner H. … WebCimetidine, 1,200 mg/day, significantly decreased theophylline clearance by 36% (range, 22% to 49%) and increased the mean elimination half-life from 5.7 hours …

Cimetidine: Uses & Side Effects Cleveland Clinic

WebJan 11, 2024 · Coadministration with drugs that decrease theophylline clearance (eg, cimetidine, ciprofloxacin, and erythromycin and other macrolides): 0.2-0.3 mg/kg/hr IV or orally (extended release) ... Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this drug, tell your doctor or pharmacist of all the … WebThere are 7 disease interactions with theophylline which include: PUD renal dysfunction seizure disorders GERD hemodialysis reduced clearance tachyarrhythmias Report … grace dodge hotel washington dc https://shopdownhouse.com

Cimetidine-Theophylline Interaction: Effects of Age and …

WebDrug Interactions Cytochrome P450 Inhibition Strong and Moderate Inhibitors of CYP3A4 or CYP2D6 The effects of ketoconazole (a strong inhibitor of CYP3A4) at 400 mg once daily for 5 days on the pharmacokinetics of a single tamsulosin hydrochloride capsule 0.4 mg dose was investigated in 24 healthy volunteers (age range 23 to 47 years). WebThis study compared the effects of diet and cimetidine on theophylline metabolism and examined interactions between these effects. Twelve men received a high-protein diet for 15 days and at another time a high-carbohydrate diet also for 15 days. Cimetidine, 800 mg daily at bedtime, was administered on days 10 through 15 of each dietary period. WebDrug Interactions: What You Need to Know By Evan Starkman Medically Reviewed by Joshua Conrad, PharmD What Are Drug Interactions? What Are the 3 Types of Drug … grace douthit

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Cimetidine and theophylline drug interaction

Diet and cimetidine induce comparable changes in theophylline …

WebCimetidine belongs to a class of drugs commonly called H2 blockers. It works by reducing the amount of acid in your stomach. ... theophylline, among others. Since cimetidine reduces the amount of ... WebTheophylline; Warfarin; This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Cimetidine and theophylline drug interaction

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WebApr 14, 2024 · HIV Drug Interactions. Interaction Checker. Apps. Download from the AppStore. ... Cidofovir Cilazapril Cimetidine Ciprofloxacin Cisapride Cisatracurium Cisplatin Citalopram Clarithromycin Clavulanic ... Terazosin Terbinafine Terbutaline Terfenadine Terlipressin Tesamorelin Testosterone Tetracaine Tetracyclines Thalidomide … WebThis interaction may be worse if you have heart failure, liver disease, kidney disease, or are on large doses of a theophylline derivative.Your healthcare professionals may already be aware of ...

WebDec 13, 2012 · Clinically important interactions are predominantly manifested in those drugs which have a narrow therapeutic index (e.g. Phenytoin, warfarin, theophylline). The interaction leads to higher steady-state blood concentrations and hence increases the incidence of side effects and toxicity. Adverse effects of such interactions can be … WebSee the list of drugs that interact with Theophylline. Includes information on severity of interaction and the level of evidence for it. ... Drug interaction information. Severe interactions are highlighted with a red marker. ... Cimetidine increases the concentration of Theophylline. Manufacturer advises adjust dose. Severity: Severe. Evidence ...

http://origin-www.webmd.com/drugs/2/drug-14245/thsc-cimetidine-oral/details/list-interaction-details/dmid-62/dmtitle-cimetidine-theophylline-derivatives/intrtype-drug WebAfter intravenous administration of cimetidine, the majority of the parent drug (58-77%) is eliminated unchanged in the urine. 2,7 Cimetidine’s primary metabolite is cimetidine sulfoxide and represents an estimated …

WebSearch for drug interactions with our API. Drug Allergy. ... non-bronchodilator prophylactic effects). Mechanism of action. Theophylline relaxes the smooth muscle of the bronchial airways and pulmonary …

WebFeb 1, 1983 · The effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was administered every six hours for three days (AX then aminophylline (200 mg) and cimetidine (300 mg) were administered every six hours for seven days (A-CX Multiple … chilled noncontact water coolerWebMar 1, 1983 · The effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was administered every six hours ... chilled number 15WebAug 25, 2024 · Severe interactions of cimetidine include: astemizole; cisapride; dofetilide; eliglustat; lomitapide; pimozide; terfenadine; Cimetidine has serious interactions with at … grace dove ethnicityWebcimetidine theophylline. Applies to: cimetidine and theophylline. Using theophylline together with cimetidine may increase the effects of theophylline. Contact your doctor if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, … gracedowntown.org/docsWebMay 8, 2024 · Warfarin's hepatic metabolism and protein binding are the most common mechanisms for the occurrence of drug-drug interactions. Warfarin is metabolized via the cytochrome P450 system by CYP 2C9, 1A2, and 3A4. It is a racemic mixture, with the S-enantiomer being 2.7 to 3.8 times more potent than the R-enantiomer. gracedowntown.churchWebThe effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was … grace dove body measurementsWebPhenytoin increases theophylline clearance by increasing microsomal enzyme activity: Serum theophylline and phenytoin concentrations decrease about 40 percent: … grace drilling company