Irf8 genecards
WebOct 4, 2024 · IRF8, or ICSBP, is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. The family also includes IRF1 ( 147575 ), IRF2 ( 147576 ), and ISGF3 (see … WebProtein Interferon regulatory factor 8 Gene Irf8 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 424 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function
Irf8 genecards
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Web(Click on the icon in the table below to see search hit context) WebMar 21, 2024 · IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma. Global assessment of IRF8 as a novel cancer biomarker. Predicting the …
WebJan 14, 2024 · MalaCards Gene Search: IRF8 Diseases sorted by gene-association score: immunodeficiency 32a, mycobacteriosis, autosomal dominant* (1650), immunodeficiency …
WebIRF8 is a Reliable Monoblast Marker for Acute Monocytic Leukemias. PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome via Regulating Its Expression in Human … WebIRF8: Interferon Regulatory Factor 8: Protein Coding: Q02556: 52: GC16P085898: 104.12: 2: FOXF1: Forkhead Box F1: Protein Coding: Q12946: 48: GC16P086510: 13.39: 3: …
WebNov 17, 2024 · IRF8 R294C mice were crossed with C57BL/6 wild-type female for at least three generations to eliminate the vertical transmission of Murine Leukemia Virus (MuLV). Progenies were crossed to generate the mice carrying homozygous alleles for the mutation, and all the mice were used at the age of 8–12 weeks.
WebGeneCards Team; Log In / Sign Up; My Genes; Showing 25 of 1,697 results for acap1 Search Time: 0 ms in NEW (Click on the icon in the table below to see search hit context) Showing of 1,697 Results for acap1 Search Time: 0 ms. Export Show: Symbol Description Category UniProt ID GIFtS GC id Score ... someone required in union to get batsman outIn myeloid cells, IRF8 regulates the expression of Bax and Fas to regulate apoptosis. In chronic myelogenous leukemia (CML), IRF8 regulates acid ceramidase to mediate CML apoptosis. IRF8 is highly expressed in myeloid cells and was originally identified in as a critical lineage-specific transcription factor for myeloid cell differentiation, recent studies, however, have shown that IRF8 is also constitutively expressed in non-hematopoietic cancer cells, albeit at a lower leve… someone rickrolled the super bowlWebMar 29, 2024 · Detroit, city, seat of Wayne county, southeastern Michigan, U.S. It is located on the Detroit River (connecting Lakes Erie and St. Clair) opposite Windsor, Ontario, … small business week mayWebFeb 15, 2008 · IRF8 binds to certain DNA motifs such as ISRE and Ets/IRF composite elements by interacting with partner proteins that include IRF members and Ets family proteins. 12, 15 Although IRF8 can regulate gene expression through other mechanisms, the interaction with partners is thought to be a critical requirement for macrophage … someone right to workWebMar 25, 2024 · IRF8 has also been found to be expressed and functional in non-hematopoietic cells such as epithelial cells [ 7, 8 ]. Studies of IRF8 mRNA levels in normal human colon and colorectal carcinoma (CRC) revealed that IRF8 is downregulated in tumor tissues as compared to non-malignant counterpart tissues. small business weekly magazineWebNov 15, 2008 · IRF8 is known to bind to any of 4 distinct target sequences in genes subject to transcriptional activation or repression by IRF8. 29 Studies of the regulatory sequences of Sfpi1, which encodes PU.1, identified 2 possible IRF8 target sites. someone riding a motorcycleWebIRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. [5] someone riding an ostrich